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Granulation Isolator

FabLife offers containment solutions for wet and dry granulation for processes involving potent OEB 4 or OEB5 products. The process within the isolator must be optimal to safeguard the operator and the environment. The ergonomically built negative pressure chamber safely contains the products during processing with glove ports for easy access. Material is transferred safely in and out of the isolator through the pass box or antechamber.

Granulation equipment, including sifter, RMG, FBD, mill and blender, are all contained in one isolator in capacities ranging from 200gms to 15kg (blend batch to 30kg) FabLife's Split Butterfly Valve dispenses tablets into IBC bins or polybags. Integrate with processing equipment for optimal performance and safety.


  • Robustly constructed in SS 316L with H14 HEPA filtration for inlet air and double HEPA filtration for exhaust

  • Optional room air intake and dedicated air handling unit for temperature and humidity management

  • Safe changing of HEPA filters

  • Inline exhaust scrubber for exhaust air treatment

  • Customizable ergonomics

  • Standard configuration includes one Pass Box (2 Glove Ports) and main chamber (4 Glove Ports), and a glove integrity tester. Multiple chamber configuration options are available

  • Enclosed dispensing into blender bins or product containers

  • Transfer routes through RTP

  • In situ chamber washing and drying; drain collection cachepot for safe handling

  • Waste liner port for waste bag discharge

  • Password protection for different authorisation levels

  • PLC-operated drum loader

  • Optional IPC SCADA 21CFR for high-grade integration and compliance

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